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Chiefs vs. Bills Prediction, Player Props, Picks & Odds for Today, 1/21

The Wild Card Round of the NFL playoffs produced plenty of newsworthy results but little drama. Will the Divisional Round give football fans more competitive contests? Well, the last game of the weekend on Sunday evening has all the makings of a thriller. The Kansas City Chiefs and Buffalo Bills will renew their recent postseason rivalry, this time in Buffalo with a spot in the AFC Championship on the line.

Our experts have examined the Chiefs vs. Bills odds for Sunday’s showdown and have come up with their best Texans vs. Ravens prediction.

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KANSAS CITY CHIEFS VS. BUFFALO BILLS PREDICTION: Buffalo Bills -2.5 (-120 at FanDuel Sportsbook)

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Kansas City Chiefs vs. Buffalo Bills Prediction for Today's Divisional Round Game

Our experts’ first Chiefs vs. Bils prediction is on the home team to cover a -2.5 point spread.

The Bills have suffered some well-documented playoff setbacks against the Chiefs in recent years, but those games were played in Kansas City. Buffalo actually won at Arrowhead Stadium earlier this season by a 20-17 margin, which is why it is the No. 2 seed behind Baltimore (Kansas City is No. 3) and is able to host the playoff showdown this time around.

Once 6-6, the Bills have suddenly become the hottest team in the NFL. They ended the regular season with five consecutive victories to steal the AFC East crown from the Miami Dolphins. Head coach Sean McDermott’s squad proceeded to take care of the Pittsburgh Steelers without any real issue in the Wild Card Round last weekend. Now Buffalo faces a Kansas City club that is not the same as it was in its recent Super Bowl-winning campaigns. Tyreek Hill is gone and Patrick Mahomes is getting nowhere near the help from his offense that he used to enjoy. On the other side of the ball, Josh Allen started the season a little slow but is now performing at an MVP level.

As such, Buffalo -2.5 is our favorite Chiefs vs. Bills prediction.

Player Prop Bets & Picks for Chiefs vs. Bills, Featuring Patrick Mahomes and Josh Allen

If you are looking for more Chiefs vs. Bills best bets, you have come to the right place. In addition to the Chiefs vs. Bills prediction listed above, our experts also like a pair of Chiefs vs. Bills player prop bets. Mahomes going over 4.5 rushing attempts (-120 at FanDuel Sportsbook) and Allen scoring a touchdown (-120 at FanDuel Sportsbook) look like strong plays.

Mahomes has exceeded 4.5 carries in all three of his Super Bowl appearances and he also went over it in a 2021 playoff game against Buffalo. In the most important situations, the star quarterback is not afraid to tuck it and run himself. Bills defensive tackle Ed Oliver had three QB hits last week against Pittsburgh. Pressure from Oliver up the middle would Mahomes outside the pocket to make plays with his feet.

Allen has scored a whopping 15 rushing touchdowns in the regular season. Unsurprisingly, he also found the endzone with his legs last weekend against Pittsburgh. Count on Allen scoring yet again, just as he did in Kansas City on December 10.

Secure $150 in Bonus Bets at FanDuel With a $5 Bet on Chiefs vs. Bills

You can back our experts’ Chiefs vs. Bills prediction or any of our Chiefs vs. Bills best bets after signing up for a new account at FanDuel Sportsbook. FanDuel is without question one of the most user-friendly and all-around best sports betting platforms in the industry, offering countless betting options in more than a dozen markets.

After registering for a new FanDuel account, you can take advantage of a generous welcome bonus. After signing up, simply make a deposit and then wager at least $5 on any sports market. It can be on our experts’ Chiefs vs. Bills prediction, any of our Chiefs vs. Bills best bets, or any other Chiefs vs. Bills odds available at FanDuel Sportsbook.

Once you have made that initial bet, you will get $150 in bonus bets regardless of whether that first wager wins or loses.

Betting Odds, Lines and Spreads for Chiefs vs. Bills With FanDuel Sportsbook

Before making your Chiefs vs. Bills prediction, it is important to be aware of the Chiefs vs. Bills odds.

Buffalo is a -2.5 favorite at FanDuel Sportsbook, making Kansas City a +2.5 underdog. On those lines, the Bills are priced at -120 while the Chiefs come with +100 odds. That means a $12 bet on the Bills is successful and returns $10 of profit if they win by at least three points. A $10 wager on the Chiefs gets you $10 in winnings if they either win outright or lose by no more than two points.

The game total, or over/under, is set at 45.5 points and both sides are priced at -110. That means an $11 wager on the over is successful and nets $10 in winnings if the two teams combine for at least 46 points. An $11 bet on the under returns $10 of profit if no more than 45 points are scored.

Injury report for Chiefs vs. Bills today, 1/21

It would also be wise to be familiar with the injury report before making a Chiefs vs Bills prediction.

For Kansas City, among the players listed as out for Sunday are OT Wanya Morris (concussion), WR Skyy Moore (knee) and DT Derrick Nnadi (tricep). WR Kadarius Toney (ankle) and WR Justyn Ross (hamstring are questionable). Buffalo will be without WR Gabe Davis (knee), S Taylor Rapp (calf), CB Christian Benford (knee) and LB Baylon Spector (back). CB Rasul Douglas (knee), CB Taron Johnson (concussion), LB Terrel Bernard (ankle) and P Sam Martin (hamstring) are questionable.

Kansas City vs. Buffalo game: Start time

The Chiefs and Bills will kick off on Sunday, January 21 at 6:30 pm ET. CBS is televising the game. Make sure you sign up at FanDuel Sportsbook in time to back our Chiefs vs. Chiefs best bets!

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